[Perioperative management of the brain-dead organ donor : Anesthesia between ethics and evidence].
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DOI: 10.1007/s00101-021-01065-9
Abstract: BACKGROUND The number of organs donated after brain death in Germany is far lower than the demand. This underlines the importance of providing the brain-dead donor with optimal medical care throughout the donation process to… read more here.
Keywords: organ protective; evidence; donor; management ... See more keywords
Organ-Protective Effects and the Underlying Mechanism of Dexmedetomidine
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DOI: 10.1155/2020/6136105
Abstract: Dexmedetomidine (DEX) is a highly selective α2 adrenergic receptor (α2AR) agonist currently used in clinical settings. Because DEX has dose-dependent advantages of sedation, analgesia, antianxiety, inhibition of sympathetic nervous system activity, cardiovascular stabilization, and significant… read more here.
Keywords: effects underlying; dex; organ protective; underlying mechanism ... See more keywords
Decay-Accelerating Factor Creates an Organ-Protective Phenotype after Hemorrhage in Conscious Rats
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DOI: 10.3390/ijms232113563
Abstract: Preclinical and clinical studies have shown that traumatic hemorrhage (TH) induces early complement cascade activation, leading to inflammation-associated multiple-organ dysfunction syndrome (MODS). Several previous studies have demonstrated the beneficial effects of complement inhibition in anesthetized… read more here.
Keywords: hemorrhage; decay accelerating; organ protective; accelerating factor ... See more keywords