Multiphoton-Guided Creation of Complex Organ-Specific Microvasculature.
Sign Up to like & getrecommendations! Published in 2021 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202100031
Abstract: Engineering functional human tissues in vitro is currently limited by difficulty replicating the small caliber, complex connectivity, cellularity, and 3D curvature of the native microvasculature. Multiphoton ablation has emerged as a promising technique for fabrication… read more here.
Keywords: creation; organ specific; perfusion; multiphoton ... See more keywords
Organ‐Specific Responses to Nivolumab Plus Ipilimumab in Advanced Hepatocellular Carcinoma: A Multicenter, Retrospective Study
Sign Up to like & getrecommendations! Published in 2025 at "Cancer Medicine"
DOI: 10.1002/cam4.70997
Abstract: Immune checkpoint inhibitor (ICI) monotherapy elicits limited intrahepatic responses in patients with advanced hepatocellular carcinoma (HCC). Here, we investigate the organ‐specific objective response rate (OSORR) of nivolumab plus ipilimumab (Nivo/Ipi) combination treatment, considering prior ICI… read more here.
Keywords: organ specific; plus ipilimumab; advanced hepatocellular; hepatocellular carcinoma ... See more keywords
Extracellular vesicles in the development of organ‐specific metastasis
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.12125
Abstract: Abstract Distant organ metastasis, often termed as organotropic metastasis or metastatic organotropism, is a fundamental feature of malignant tumours and accounts for most cancer‐related mortalities. This process is orchestrated by many complex biological interactions and… read more here.
Keywords: extracellular vesicles; organ specific; organotropic metastasis; development organ ... See more keywords
Reconstruction of three-dimensional tomographic patient models for radiation dose modulation in CT from two scout views using deep learning.
Sign Up to like & getrecommendations! Published in 2021 at "Medical physics"
DOI: 10.1002/mp.15414
Abstract: BACKGROUND A tomographic patient model is essential for radiation dose modulation in x-ray computed tomography (CT). Currently, two-view scout images (also known as topograms) are used to estimate patient models with relatively uniform attenuation coefficients.… read more here.
Keywords: scout; radiation dose; patient; scoutct net ... See more keywords
Organ-specific response to nivolumab in patients with non-small cell lung cancer (NSCLC)
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Immunology, Immunotherapy"
DOI: 10.1007/s00262-018-2239-4
Abstract: BackgroundResponse to immune checkpoint inhibitors depends on tumor intrinsic properties and also on host factors in the tumour microenvironment including the presence of immune cells (IC). We hypothesized that nivolumab efficacy varies across different metastatic… read more here.
Keywords: specific response; response; organ specific; cell lung ... See more keywords
Diversity of Organism-Wide and Organ-Specific Endothelial Cells
Sign Up to like & getrecommendations! Published in 2020 at "Current Cardiology Reports"
DOI: 10.1007/s11886-020-1275-9
Abstract: Purpose of Review Endothelial cells are of great importance in many types of diseases including the coronary artery diseases in heart and stroke in brain. In this review, we explore the heterogeneity among endothelial cells… read more here.
Keywords: wide organ; organism wide; organ specific; ecs ... See more keywords
Microphysiological Systems as Organ-Specific In Vitro Vascular Models for Disease Modeling
Sign Up to like & getrecommendations! Published in 2024 at "BioChip Journal"
DOI: 10.1007/s13206-024-00152-4
Abstract: The vascular system, essential for human physiology, is vital for transporting nutrients, oxygen, and waste. Since vascular structures are involved in various disease pathogeneses and exhibit different morphologies depending on the organ, researchers have endeavored… read more here.
Keywords: organ specific; vitro vascular; vascular models; specific vitro ... See more keywords
Effects of UV-A radiation on organ-specific accumulation and gene expression of isoflavones and flavonols in soybean sprout.
Sign Up to like & getrecommendations! Published in 2021 at "Food chemistry"
DOI: 10.1016/j.foodchem.2020.128080
Abstract: Organ-specific flavonoid destination in soybean sprouts following UV irradiation is still unclear although the metabolic pathway of flavonoid synthesis and UV responded flavonoid accumulation have been well investigated. We report the identification of organ-specific localization… read more here.
Keywords: expression; organ specific; expression isoflavones; accumulation ... See more keywords
Organ-specific differences in endogenous phytohormone and antioxidative responses in potato upon PSTVd infection.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of plant physiology"
DOI: 10.1016/j.jplph.2018.10.027
Abstract: Although structurally simple, viroids can trigger numerous changes in host plants and cause loss of yield in agronomically important crops. This study investigated changes in the endogenous status of phytohormones and antioxidant enzyme activity in… read more here.
Keywords: organ specific; pstvd infection; infection; endogenous phytohormone ... See more keywords
Clinical and laboratory skin biomarkers of organ-specific diseases
Sign Up to like & getrecommendations! Published in 2019 at "Mechanisms of Ageing and Development"
DOI: 10.1016/j.mad.2018.08.003
Abstract: Intense research during the last few years has elucidated a number of mechanisms of the complex human aging process. Among the body organs, skin has a distinguished role in aging perception both because it constitutes… read more here.
Keywords: organ specific; skin; laboratory skin; specific diseases ... See more keywords
RACK1 is an organ-specific prognostic predictor in OSCC.
Sign Up to like & getrecommendations! Published in 2018 at "Oral oncology"
DOI: 10.1016/j.oraloncology.2017.10.025
Abstract: OBJECTIVES This study aims to verify that RACK1 is an organ-specific prognostic predictor in patients with oral squamous cell carcinoma (OSCC). EXPERIMENTAL DESIGN The RACK1 expression level was assessed by immunohistochemistry (IHC) in a total… read more here.
Keywords: specific prognostic; organ specific; rack1; predictor ... See more keywords