A Compendium of Genetic Modifiers of Mitochondrial Dysfunction Reveals Intra-organelle Buffering
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DOI: 10.1016/j.cell.2019.10.032
Abstract: Mitochondrial dysfunction is associated with a spectrum of human conditions, ranging from rare, inborn errors of metabolism to the aging process. To identify pathways that modify mitochondrial dysfunction, we performed genome-wide CRISPR screens in the… read more here.
Keywords: organelle buffering; genetic modifiers; intra organelle; dysfunction ... See more keywords