Defective Ribosome Recycling: A Bridge Between Translation Fidelity, Organelle Dysfunction, and Diseases
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DOI: 10.1002/bies.70054
Abstract: Ribosome recycling is a fundamental biological process crucial for cellular health. Defective recycling disrupts ribosome biogenesis and organelle function, particularly in mitochondria, contributing to ribosomopathies, neurodegenerative diseases, and cancer. While not directly linked to human… read more here.
Keywords: fidelity organelle; organelle dysfunction; ribosome; ribosome recycling ... See more keywords
Loss of AMPK activity induces organelle dysfunction and oxidative stress during oocyte aging
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DOI: 10.1186/s13062-024-00471-4
Abstract: Background Oocyte quality is critical for the mammalian reproduction due to its necessity on fertilization and early development. During aging, the declined oocytes showing with organelle dysfunction and oxidative stress lead to infertility. AMP-activated protein… read more here.
Keywords: ampk activity; organelle dysfunction; oxidative stress; ampk ... See more keywords