Perturbing Organelle‐Level K+/Ca2+ Homeostasis by Nanotherapeutics for Enhancing Ion‐Mediated Cancer Immunotherapy
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DOI: 10.1002/adma.202416574
Abstract: Intracellular ions are involved in numerous pivotal immune processes, but the precise regulation of these signaling ions to achieve innovative immune therapeutic strategies is still a huge challenge. Here, an ion‐mediated immunotherapy agent (IMIA) is… read more here.
Keywords: ca2 homeostasis; homeostasis; ion mediated; organelle level ... See more keywords
Organelle-Level Trafficking and Metabolism Kinetics for Redox-Responsive Paclitaxel Prodrug Nanoparticles Characterized by Experimental and Modeling Analysis.
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DOI: 10.1021/acsnano.4c09704
Abstract: Redox-responsive self-assembled prodrug nanoparticles have received extensive attention for their high loading efficiency and environmentally responsive properties. However, the intracellular metabolism and transportation kinetics were poorly understood, which limited the rational design and development of… read more here.
Keywords: redox responsive; prodrug nanoparticles; organelle level; metabolism ... See more keywords