Role of self-organising myddosome oligomers in inflammatory signalling by Toll-like receptors
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DOI: 10.1186/s12915-019-0637-5
Abstract: A paper published in BMC Biology characterises biophysically oligomeric and filamentous structures formed spontaneously by the Toll-like receptor signalling adaptor MyD88. Naturally occurring mutants of MyD88 that cause immunodeficiency are unable to form these structures.… read more here.
Keywords: self organising; toll like; inflammatory signalling; organising myddosome ... See more keywords