The 3D Organization of Chromatin Colors in Mammalian Nuclei.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1390-0_17
Abstract: While many computational methods have been proposed for 3D chromosome reconstruction from chromosomal contact maps, these methods are rarely used for the interpretation of such experimental data, in particular Hi-C data. We posit that this… read more here.
Keywords: methodology; chromatin; mammalian nuclei; chromatin colors ... See more keywords
Dynamic Organization of Chromatin Domains Revealed by Super-Resolution Live-Cell Imaging.
Sign Up to like & getrecommendations! Published in 2017 at "Molecular cell"
DOI: 10.1016/j.molcel.2017.06.018
Abstract: The eukaryotic genome is organized within cells as chromatin. For proper information output, higher-order chromatin structures can be regulated dynamically. How such structures form and behave in various cellular processes remains unclear. Here, by combining… read more here.
Keywords: organization chromatin; cell; super resolution; dynamic organization ... See more keywords
Spatial Organization of Chromatin: Emergence of Chromatin Structure During Development.
Sign Up to like & getrecommendations! Published in 2021 at "Annual review of cell and developmental biology"
DOI: 10.1146/annurev-cellbio-032321-035734
Abstract: Nuclei are central hubs for information processing in eukaryotic cells. The need to fit large genomes into small nuclei imposes severe restrictions on genome organization and the mechanisms that drive genome-wide regulatory processes. How a… read more here.
Keywords: spatial organization; organization chromatin; biology; organization ... See more keywords
Spatial Organization of Chromatin: Transcriptional Control of Adaptive Immune Cell Development
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.633825
Abstract: Higher-order spatial organization of the genome into chromatin compartments (permissive and repressive), self-associating domains (TADs), and regulatory loops provides structural integrity and offers diverse gene regulatory controls. In particular, chromatin regulatory loops, which bring enhancer… read more here.
Keywords: spatial organization; organization chromatin; gene; immune cell ... See more keywords