The Three-Dimensional Organization of Mammalian Genomes.
Sign Up to like & getrecommendations! Published in 2017 at "Annual review of cell and developmental biology"
DOI: 10.1146/annurev-cellbio-100616-060531
Abstract: Animal development depends on not only the linear genome sequence that embeds millions of cis-regulatory elements, but also the three-dimensional (3D) chromatin architecture that orchestrates the interplay between cis-regulatory elements and their target genes. Compared… read more here.
Keywords: three dimensional; mammalian genomes; organization mammalian; dimensional organization ... See more keywords
Sparse genetic tracing reveals regionally specific functional organization of mammalian nociceptors
Sign Up to like & getrecommendations! Published in 2017 at "eLife"
DOI: 10.7554/elife.29507
Abstract: The human distal limbs have a high spatial acuity for noxious stimuli but a low density of pain-sensing neurites. To elucidate mechanisms underlying regional differences in processing nociception, we sparsely traced non-peptidergic nociceptors across the… read more here.
Keywords: genetic tracing; organization mammalian; plantar paw; functional organization ... See more keywords