Differentiation of the tumor microenvironment: are CAFs the Organizer?
Sign Up to like & getrecommendations! Published in 2021 at "Trends in cell biology"
DOI: 10.1016/j.tcb.2021.11.008
Abstract: Cancers contain a suite of genetically stable cells within an extracellular matrix, collectively termed the tumor microenvironment (TME). The TME strongly influences disease outcome for patients. Gleaning clues from the literature, we propose that the… read more here.
Keywords: differentiation tumor; differentiation; organizer; tumor microenvironment ... See more keywords
Establishment and activity of the D quadrant organizer in the marine gastropod Crepidula fornicata.
Sign Up to like & getrecommendations! Published in 2017 at "Developmental biology"
DOI: 10.1016/j.ydbio.2017.09.003
Abstract: During development in metazoan embryos, the fundamental embryonic axes are established by organizing centers that influence the fates of nearby cells. Among the spiralians, a large and diverse branch of protostome metazoans, studies have shown… read more here.
Keywords: organizer; quadrant organizer; crepidula fornicata; polar lobe ... See more keywords
Interplay between Lefty and Nodal signaling is essential for the organizer and axial formation in amphioxus embryos.
Sign Up to like & getrecommendations! Published in 2019 at "Developmental biology"
DOI: 10.1016/j.ydbio.2019.08.006
Abstract: The organizer is an essential signaling center required for axial formation during vertebrate embryonic development. In the basal chordate amphioxus, the dorsal blastopore lip of the gastrula has been proposed to be homologous to the… read more here.
Keywords: organizer; axial formation; amphioxus embryos; lefty nodal ... See more keywords
A new A-P compartment boundary and organizer in holometabolous insect wings
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-16553-5
Abstract: Decades of research on the highly modified wings of Drosophila melanogaster has suggested that insect wings are divided into two Anterior-Posterior (A-P) compartments separated by an axis of symmetry. This axis of symmetry is created… read more here.
Keywords: axis symmetry; new compartment; compartment boundary; organizer ... See more keywords
Bighead is a Wnt antagonist secreted by the Xenopus Spemann organizer that promotes Lrp6 endocytosis
Sign Up to like & getrecommendations! Published in 2018 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.1812117115
Abstract: Significance The early frog embryo provides a classical model system for the isolation of secreted molecules that regulate long-range cell–cell communication. Extensive screens of a region with embryonic induction activity, called Spemann organizer, have revealed… read more here.
Keywords: wnt; organizer; bighead; endocytosis ... See more keywords
The Impact of Organizer Market Structure on Participant Entry Behavior in a Multi-Tournament Environment
Sign Up to like & getrecommendations! Published in 2023 at "Games"
DOI: 10.3390/g14010004
Abstract: A multi-tournament environment is analyzed, focusing on the impact of organizer market structure on agent entry behavior. Two high ability agents first decide which tournament to enter (with fields then filled by low ability agents).… read more here.
Keywords: ability; multi tournament; market; high ability ... See more keywords