Development of a Platform To Enable Efficient Permeability Evaluation of Novel Organo-Peptide Macrocycles.
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DOI: 10.1021/acsmedchemlett.9b00036
Abstract: As more macrocycle structures are utilized to drug intracellular targets, new platforms are needed to facilitate the discovery of cell permeable compounds in this unique chemical space. Herein, a method is disclosed that allows for… read more here.
Keywords: permeability evaluation; novel organo; organo peptide; evaluation novel ... See more keywords