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   Articles with "organocatalysis" as a keyword



The Integral Role of Conjugate Acids in Brønsted Base‐Catalyzed Regiodivergent Synthesis

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recommendations! Published in 2024 at "ChemCatChem"

DOI: 10.1002/cctc.202400405

Abstract: Catalyst‐controlled diversity‐oriented synthesis (CatDOS) is an important research area for expanding molecular complexities and achieving high atomic economics. Many regiodivergent syntheses have been achieved through metal catalysis, covalent organocatalysis, and non‐covalent organocatalysis by controlling the… read more here.

Keywords: nsted base; regioselectivity; organocatalysis; conjugate acids ... See more keywords

Exploring Molecular Complexity by N-Heterocyclic Carbene Organocatalysis: New Activation and Reaction Diversity.

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recommendations! Published in 2022 at "Chemical record"

DOI: 10.1002/tcr.202200219

Abstract: The development of catalytic synthetic approaches towards molecular complexity from simple materials continues to be an ultimate goal in synthetic chemistry. Over the past decades, N-heterocyclic carbene (NHC) organocatalysis has been extensively investigated to provide… read more here.

Keywords: new activation; molecular complexity; organocatalysis; complexity ... See more keywords

Synthesis of enantioenriched α-heteroatom functionalised aldehydes by chiral organocatalysis and their synthetic applications

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recommendations! Published in 2021 at "Organic Chemistry Frontiers"

DOI: 10.1039/d1qo00101a

Abstract: Asymmetric organocatalysis is a versatile method for the enantioselective α-functionalisation of aldehydes. The synthetic scope for chiral α-heteroatom substituted aldehydes is examined including their applications in synthesis. read more here.

Keywords: organocatalysis; synthesis enantioenriched; enantioenriched heteroatom; heteroatom ... See more keywords

Heterogeneous organocatalysis: the proline case

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recommendations! Published in 2025 at "RSC Advances"

DOI: 10.1039/d5ra02331a

Abstract: Asymmetric catalysis has allowed organic chemists to synthesize chiral molecules, such as amino acids, nucleic acids, sugars, and drugs. To achieve this, it is common to use a chiral catalyst to selectively accelerate the reaction.… read more here.

Keywords: heterogeneous organocatalysis; organocatalysis; methodology; proline ... See more keywords

Asymmetric Organocatalysis: A Survival Guide to Medicinal Chemists

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recommendations! Published in 2022 at "Molecules"

DOI: 10.3390/molecules28010271

Abstract: Majority of drugs act by interacting with chiral counterparts, e.g., proteins, and we are, unfortunately, well-aware of how chirality can negatively impact the outcome of a therapeutic regime. The number of chiral, non-racemic drugs on… read more here.

Keywords: medicinal chemists; organocatalysis survival; survival guide; chemistry ... See more keywords