Exploring Molecular Complexity by N-Heterocyclic Carbene Organocatalysis: New Activation and Reaction Diversity.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical record"
DOI: 10.1002/tcr.202200219
Abstract: The development of catalytic synthetic approaches towards molecular complexity from simple materials continues to be an ultimate goal in synthetic chemistry. Over the past decades, N-heterocyclic carbene (NHC) organocatalysis has been extensively investigated to provide… read more here.
Keywords: new activation; molecular complexity; organocatalysis; complexity ... See more keywords
Synthesis of enantioenriched α-heteroatom functionalised aldehydes by chiral organocatalysis and their synthetic applications
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DOI: 10.1039/d1qo00101a
Abstract: Asymmetric organocatalysis is a versatile method for the enantioselective α-functionalisation of aldehydes. The synthetic scope for chiral α-heteroatom substituted aldehydes is examined including their applications in synthesis. read more here.
Keywords: organocatalysis; synthesis enantioenriched; enantioenriched heteroatom; heteroatom ... See more keywords
Asymmetric Organocatalysis: A Survival Guide to Medicinal Chemists
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DOI: 10.3390/molecules28010271
Abstract: Majority of drugs act by interacting with chiral counterparts, e.g., proteins, and we are, unfortunately, well-aware of how chirality can negatively impact the outcome of a therapeutic regime. The number of chiral, non-racemic drugs on… read more here.
Keywords: medicinal chemists; organocatalysis survival; survival guide; chemistry ... See more keywords