Unprecedented Multicomponent Organocatalytic Synthesis of Propargylic Esters via CO2 Activation
Sign Up to like & getrecommendations! Published in 2019 at "ChemCatChem"
DOI: 10.1002/cctc.201900207
Abstract: An efficient and straightforward organocatalytic method for the direct, multicomponent carboxylation of terminal alkynes with CO2 and organochlorides, towards propargylic esters, is reported for the first time. 1,3‐Di‐tert‐butyl‐1H‐imidazol‐3‐ium chloride, a simple, widely‐available, stable, and cost‐efficient… read more here.
Keywords: unprecedented multicomponent; synthesis propargylic; propargylic esters; multicomponent ... See more keywords
Organocatalytic Synthesis of Chiral Halogenated Compounds.
Sign Up to like & getrecommendations! Published in 2023 at "Chemical record"
DOI: 10.1002/tcr.202300061
Abstract: This account summarizes our recent efforts in the enantioselective organocatalytic synthesis of chiral halogenated compounds. The enantioselective α-halogenation of aldehydes, decarboxylative chlorination of β-keto acids, and enantioselective C-C bond formation at the trifluoromethylated prochiral carbon… read more here.
Keywords: organocatalytic synthesis; chiral halogenated; synthesis chiral; halogenated compounds ... See more keywords
Organocatalytic Synthesis of cis-2,3-Aziridine Aldehydes by a Postreaction Isomerization.
Sign Up to like & getrecommendations! Published in 2017 at "Organic letters"
DOI: 10.1021/acs.orglett.7b02634
Abstract: An unprecedented organocatalytic cis-selective aziridination of α,β-unsaturated aldehydes is described. The strategy utilizes postreaction isomerization as a key step. Our study demonstrates that by a proper choice of structural features of reagents and the catalyst… read more here.
Keywords: postreaction isomerization; organocatalytic synthesis; synthesis cis; cis ... See more keywords
Organocatalytic Synthesis of α-Trifluoromethyl Allylboronic Acids by Enantioselective 1,2-Borotropic Migration
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.0c09923
Abstract: Chiral α-substituted allylboronic acids were synthesized by asymmetric homologation of alkenylboronic acids using CF3/TMS-diazomethanes in the presence of BINOL catalyst and ethanol. The chiral α-substituted allylboronic acids were reacted with aldehydes or oxidized to alcohols… read more here.
Keywords: allylboronic acids; enantioselective borotropic; synthesis trifluoromethyl; trifluoromethyl allylboronic ... See more keywords
Organocatalytic synthesis of enantioenriched 1,2,4-triazolines containing a chiral quaternary carbon center
Sign Up to like & getrecommendations! Published in 2017 at "RSC Advances"
DOI: 10.1039/c6ra28800f
Abstract: An efficient asymmetric cyclization reaction of amino-acid-derived isothiocyanates with azodicarboxylates is described. The chiral 1,2,4-triazolines are prepared in good yield (up to 87%) and enantioselectivities (up to 95% ee). read more here.
Keywords: containing chiral; synthesis enantioenriched; enantioenriched triazolines; triazolines containing ... See more keywords
Photo-organocatalytic synthesis of acetals from aldehydes
Sign Up to like & getrecommendations! Published in 2019 at "Green Chemistry"
DOI: 10.1039/c8gc03605e
Abstract: A mild and green photo-organocatalytic protocol for the highly efficient acetalization of aldehydes has been developed. read more here.
Keywords: photo organocatalytic; synthesis acetals; organocatalytic synthesis; chemistry ... See more keywords
Recent approaches in the organocatalytic synthesis of pyrroles
Sign Up to like & getrecommendations! Published in 2021 at "RSC Advances"
DOI: 10.1039/d1ra01690c
Abstract: Organocatalysis has emerged as one of the most important tools for the synthesis of diverse structural scaffolds, and has become one of the most important hot topics of current research. Construction of the pyrrole ring… read more here.
Keywords: synthesis; synthesis pyrroles; organocatalytic synthesis; approaches organocatalytic ... See more keywords
Recent advances and prospects in the organocatalytic synthesis of quinazolinones
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Chemistry"
DOI: 10.3389/fchem.2022.991026
Abstract: Quinazolinone, a bicyclic compound, comprises a pyrimidine ring fused at 4´ and 8´ positions with a benzene ring and constitutes a substantial class of nitrogen-containing heterocyclic compounds on account of their frequent existence in the… read more here.
Keywords: organocatalytic synthesis; advances prospects; chemistry; synthesis quinazolinones ... See more keywords