Access to Chiral Chromenones through Organocatalyzed Mannich/Annulation Sequence.
Sign Up to like & getrecommendations! Published in 2021 at "Organic letters"
DOI: 10.1021/acs.orglett.1c03010
Abstract: Herein we report an efficient and practical method to access chiral chromenones bearing one α-amino stereogenic center in the β position of the carbonyl group. The quinine-derived squaramide could efficiently promote Mannich/cycloketalization/dehydration tandem reactions between… read more here.
Keywords: organocatalyzed mannich; mannich annulation; access chiral; chromenones organocatalyzed ... See more keywords
Experimental and Computational Studies Unraveling the Peculiarity of Enolizable Oxoesters in the Organocatalyzed Mannich-Type Addition to Cyclic N-Acyl Iminium Ions
Sign Up to like & getrecommendations! Published in 2020 at "Molecules"
DOI: 10.3390/molecules25081903
Abstract: γ− and δ-Oxoesters are easily available starting materials that have been sparingly used in some organocatalyzed reactions proceeding with a high enantioselectivity. In our experimentation we found that the use of these compounds as the… read more here.
Keywords: organocatalyzed mannich; iminium ions; mannich type; cyclic acyl ... See more keywords