Articles with "organoid differentiation" as a keyword



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A single-cell multiomic analysis of kidney organoid differentiation

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Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.2219699120

Abstract: Significance During development, changes in chromatin structure regulate gene expression dynamics. A detailed understanding of gene regulatory networks will improve our understanding of organogenesis and disease mechanisms. Using single-nucleus RNA-sequencing (snRNA-seq) and assay for transposase-accessible… read more here.

Keywords: kidney organoid; organoid differentiation; single cell;