Altered energy metabolism in Fatal Familial Insomnia cerebral organoids is associated with astrogliosis and neuronal dysfunction
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DOI: 10.1371/journal.pgen.1010565
Abstract: Fatal familial insomnia (FFI) is a rare neurodegenerative disease caused by a dominantly inherited single amino acid substitution (D178N) within the prion protein (PrP). No in vitro human brain tissue model for this disease has… read more here.
Keywords: prp; energy; fatal familial; cerebral organoids ... See more keywords