Organoids as a Model to Study Infectious Disease.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7604-1_8
Abstract: The advent of the gastric organoid culture system has provided a new model to emulate native epithelial tissue in vitro. Gastric organoids grow from isolated epithelial stem cells and develop into three dimensional structures that… read more here.
Keywords: infectious disease; model study; study infectious; model ... See more keywords
Three-Dimensional Microfluidic Platform with Neural Organoids: Model System for Unraveling Synapses.
Sign Up to like & getrecommendations! Published in 2019 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.9b00654
Abstract: Unraveling the large number of various signals in the brain under the influence of physical and chemical cues that govern the formation of individual neurons, axons, dendrites, and their functional synapses during the development of… read more here.
Keywords: three dimensional; microfluidic platform; neural organoids; platform neural ... See more keywords
Fused cerebral organoids model interactions between brain regions
Sign Up to like & getrecommendations! Published in 2017 at "Nature Methods"
DOI: 10.1038/nmeth.4304
Abstract: Human brain development involves complex interactions between different regions, including long-distance neuronal migration or formation of major axonal tracts. Different brain regions can be cultured in vitro within 3D cerebral organoids, but the random arrangement… read more here.
Keywords: brain regions; cerebral organoids; organoids model; fused cerebral ... See more keywords
Cancer organoids to model therapy response
Sign Up to like & getrecommendations! Published in 2018 at "Science"
DOI: 10.1126/science.359.6378.880-d
Abstract: Organoids Cancer organoids are miniature, three-dimensional cell culture models that can be made from primary patient tumors and studied in the laboratory. Vlachogiannis et al. asked whether such “tumor-in-a-dish” approaches can be used to predict… read more here.
Keywords: drug; therapy response; cancer organoids; model therapy ... See more keywords
Patient-derived organoids model treatment response of metastatic gastrointestinal cancers
Sign Up to like & getrecommendations! Published in 2018 at "Science"
DOI: 10.1126/science.aao2774
Abstract: Cancer organoids to model therapy response Cancer organoids are miniature, three-dimensional cell culture models that can be made from primary patient tumors and studied in the laboratory. Vlachogiannis et al. asked whether such “tumor-in-a-dish” approaches… read more here.
Keywords: medicine; metastatic gastrointestinal; drug; organoids model ... See more keywords
Porcine small intestinal organoids as a model to explore ETEC–host interactions in the gut
Sign Up to like & getrecommendations! Published in 2021 at "Veterinary Research"
DOI: 10.1186/s13567-021-00961-7
Abstract: Small intestinal organoids, or enteroids, represent a valuable model to study host–pathogen interactions at the intestinal epithelial surface. Much research has been done on murine and human enteroids, however only a handful studies evaluated the… read more here.
Keywords: porcine small; small intestinal; model; host ... See more keywords
Murine Endometrial Organoids to Model Chlamydia Infection
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2020.00416
Abstract: The obligate intracellular bacterium Chlamydia trachomatis is the leading cause of bacterial sexually transmitted infections. Once internalized in host cells, C. trachomatis undergoes a biphasic developmental cycle within a membrane-bound compartment, known as the inclusion.… read more here.
Keywords: murine endometrial; endometrial organoids; infection; model ... See more keywords