Organoids to study immune functions, immunological diseases and immunotherapy.
Sign Up to like & getrecommendations! Published in 2020 at "Cancer letters"
DOI: 10.1016/j.canlet.2020.02.027
Abstract: Three-dimensional organoid culture systems show great promise as innovative physiological and pathophysiological models. Their applications in immunological research have been widely explored. For instance, immune organoids allow functional studies of immune system-related conditions, in a… read more here.
Keywords: immune functions; organoids study; study immune; functions immunological ... See more keywords
Brain Organoids to Study SARS-Cov-2 Infection of Developing CNS
Sign Up to like & getrecommendations! Published in 2021 at "Toxicology Letters"
DOI: 10.1016/s0378-4274(21)00409-4
Abstract: Early reports from Wuhan suggested that 36% of COVID-19 patients show neurological symptoms, later European studies showed as much as 60%;cases of viral encephalitis have been reported. This suggests that the virus might be neurotropic… read more here.
Keywords: organoids study; infection; brain organoids; virus ... See more keywords
Generation of vascularized brain organoids to study neurovascular interactions
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.1101/2022.01.04.474960
Abstract: The recently developed brain organoids have been used to recapitulate the processes of brain development and related diseases. However, the lack of vasculatures, which regulate neurogenesis, brain disorders, and aging process, limits the utility of… read more here.
Keywords: organoids study; brain; vascularized brain; brain organoids ... See more keywords