Beyond organoids: In vitro vasculogenesis and angiogenesis using cells from mammals and zebrafish.
Sign Up to like & getrecommendations! Published in 2017 at "Reproductive toxicology"
DOI: 10.1016/j.reprotox.2017.07.002
Abstract: The ability to culture complex organs is currently an important goal in biomedical research. It is possible to grow organoids (3D organ-like structures) in vitro; however, a major limitation of organoids, and other 3D culture… read more here.
Keywords: vascular networks; vasculogenesis angiogenesis; beyond organoids; vitro vasculogenesis ... See more keywords
Gastric organoids—an in vitro model system for the study of gastric development and road to personalized medicine
Sign Up to like & getrecommendations! Published in 2020 at "Cell Death and Differentiation"
DOI: 10.1038/s41418-020-00662-2
Abstract: Gastric cancer ranks as the fifth most common human malignancy and the third leading cause of cancer related deaths. Depending on tumor stage, endoscopic or surgical resection supported by perioperative chemotherapy is the only curative… read more here.
Keywords: medicine; vitro model; organoids vitro; development ... See more keywords
Human Brain Organoids as an In Vitro Model System of Viral Infectious Diseases
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.792316
Abstract: Brain organoids, or brainoids, have shown great promise in the study of central nervous system (CNS) infection. Modeling Zika virus (ZIKV) infection in brain organoids may help elucidate the relationship between ZIKV infection and microcephaly.… read more here.
Keywords: system; human brain; organoids vitro; brain organoids ... See more keywords
Liver Organoids as an In Vitro Model to Study Primary Liver Cancer
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24054529
Abstract: Primary liver cancers (PLC), including hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCA), are among the leading causes of cancer-related mortality worldwide. Bi-dimensional in vitro models are unable to recapitulate the key features of PLC; consequently, recent… read more here.
Keywords: liver; organoids vitro; liver organoids; vitro model ... See more keywords