Aspirin-inspired organometallic compounds: Structural characterization and cytotoxicity
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Organometallic Chemistry"
DOI: 10.1016/j.jorganchem.2017.01.016
Abstract: Abstract We report here the preparation of 2-hydroxy-4-(picolinamido)benzoic acid and its aspirin analogue 2-acetoxy-4-(picolinamido)benzoic acid. Both ligands were used to synthesize organoruthenium and -osmium complexes. The compounds were characterized by NMR spectroscopy, electrospray ionization mass… read more here.
Keywords: picolinamido benzoic; organometallic compounds; inspired organometallic; compounds structural ... See more keywords
Organometallic compounds as carriers of extraterrestrial cyanide in primitive meteorites
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-10866-x
Abstract: Extraterrestrial delivery of cyanide may have been crucial for the origin of life on Earth since cyanide is involved in the abiotic synthesis of numerous organic compounds found in extant life; however, little is known… read more here.
Keywords: compounds carriers; organometallic compounds; carriers extraterrestrial; iron cyanocarbonyl ... See more keywords
Unprecedented collateral sensitivity for cisplatin-resistant lung cancer cells presented by new ruthenium organometallic compounds
Sign Up to like & getrecommendations! Published in 2021 at "Inorganic chemistry frontiers"
DOI: 10.1039/d0qi01344g
Abstract: Platinum-based therapies continue to be the main regimen used to treat non-small cell lung cancers (NSCLC), where multidrug resistance plays a key role in treatment failure and strategies to overcome this limitation are urgently sought… read more here.
Keywords: lung; collateral sensitivity; lung cancer; organometallic compounds ... See more keywords
Mechanistic Insights into Gold Organometallic Compounds and their Biomedical Applications.
Sign Up to like & getrecommendations! Published in 2017 at "Chimia"
DOI: 10.2533/chimia.2017.308
Abstract: The application of gold in medicine is can be traced back several thousand years and Au(i) compounds have been used in the treatment of rheumatoid arthritis since the last century. Recently research into gold-based drugs… read more here.
Keywords: compounds biomedical; organometallic compounds; gold organometallic; insights gold ... See more keywords
Thiourea-Derived Chelating Ligands and Their Organometallic Compounds: Investigations into Their Anticancer Activity
Sign Up to like & getrecommendations! Published in 2020 at "Molecules"
DOI: 10.3390/molecules25163661
Abstract: Thiones have been investigated as ligands in metal complexes with catalytic and biological activity. We report the synthesis, characterization, and biological evaluation of a series of MII/III complexes of the general formulae [MII(cym)(L)Cl]X (cym =… read more here.
Keywords: organometallic compounds; chelating ligands; activity; derived chelating ... See more keywords
Selected Organometallic Compounds for Third Order Nonlinear Optical Application
Sign Up to like & getrecommendations! Published in 2019 at "Nanomaterials"
DOI: 10.3390/nano9020254
Abstract: In this paper, we present the third harmonic generation response of Znq2 (Bis-(8-hydroxyquinolinato)zinc), Cuq2 (8-Hydroxyquinoline copper(II)), and Alq3 (Tris-(8-hydroxyquinoline)aluminum) organometallic compounds. An experiment was conducted for s and p polarizations of incident beam, using the… read more here.
Keywords: compounds third; organometallic compounds; third order; order nonlinear ... See more keywords
New Organometallic Ru(II) Compounds with Lonidamine Motif as Antitumor Agents
Sign Up to like & getrecommendations! Published in 2023 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics15051366
Abstract: The combination of one molecule of organic and metal-based fragments that exhibit antitumor activity is a modern approach in the search for new promising drugs. In this work, biologically active ligands based on lonidamine (a… read more here.
Keywords: motif antitumor; lonidamine motif; antitumor; organometallic compounds ... See more keywords