Organometallic gold(III) complex [Au(Hdamp)(L14)]+ (L1 = SNS-donating thiosemicarbazone) as a candidate to new formulations against Chagas disease.
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DOI: 10.1021/acsinfecdis.8b00284
Abstract: Chagas disease remains a serious public health concern with unsatisfactory treatment outcomes due to strain-specific drug resistance and various side effects. To identify new therapeutic drugs against Trypanosoma cruzi, we evaluated both the in vitro… read more here.
Keywords: organometallic gold; gold iii; chagas disease; disease ... See more keywords
Organometallic Gold(III) Reagents for Cysteine Arylation.
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DOI: 10.1021/jacs.8b04115
Abstract: An efficient method for chemoselective cysteine arylation of unprotected peptides and proteins using Au(III) organometallic complexes is reported. The bioconjugation reactions proceed rapidly ( read more here.
Keywords: organometallic gold; gold iii; iii reagents; cysteine arylation ... See more keywords