Electrophilic Trifluoromethylâ and Fluoroalkylselenolation of Organometallic Reagents
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Organic Chemistry"
DOI: 10.1002/ejoc.201601526
Abstract: Fluoroalkylseleno groups are emerging groups that still suffer from a lack of efficient methods for introduction onto organic molecules. Herein, we describe an efficient method to perform reactions between in situ formed fluoroalkaneselenyl chlorides and… read more here.
Keywords: fluoroalkylselenolation organometallic; trifluoromethyl fluoroalkylselenolation; chemistry; electrophilic trifluoromethyl ... See more keywords
Safer solvents for reactive organometallic reagents
Sign Up to like & getrecommendations! Published in 2018 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2018.09.041
Abstract: Abstract This paper describes the use of poly(α -olefin)s (PAOs) as safer alternatives to cyclohexane, hexanes, and heptane as solvents for alkyllithium reagents. While PAOs like any alkane are flammable, PAOs do not readily catch… read more here.
Keywords: solvents reactive; safer solvents; reactive organometallic; organometallic reagents ... See more keywords
Synthesis of Unsymmetrical Ketones Using Chelation-Controlled Sequential Substitution of N-Triazinylamide/Weinreb Amide by Organometallic Reagents
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DOI: 10.1021/acsomega.2c06756
Abstract: N-(2,4-Dimethoxy-1,3,5-triazinyl)amide was found to exhibit similar behavior to N-methoxy-N-methylamide (Weinreb amide) but higher reactivity for nucleophilic substitution by organometallic reagents. Triazinylamide suppresses overaddition, leading to the formation of a tertiary alcohol by the chelating ability… read more here.
Keywords: substitution; unsymmetrical ketones; ketones using; organometallic reagents ... See more keywords
Selective Substitution of POCl 3 with Organometallic Reagents: Synthesis of Phosphinates and Phosphonates
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DOI: 10.1055/s-0037-1609435
Abstract: The selectivity of the substitution reaction of phosphoryl chloride with organometallic reagents was investigated using NMR spectroscopy. This led to the discovery that the selectivity of the substitution reaction can be tuned by choosing a… read more here.
Keywords: phosphinates phosphonates; substitution pocl; selective substitution; organometallic reagents ... See more keywords