Articles with "organotypic" as a keyword



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Organotypic platform for studying cancer cell metastasis.

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Published in 2021 at "Experimental cell research"

DOI: 10.1016/j.yexcr.2021.112527

Abstract: Metastasis is the leading cause of mortality in cancer patients. To migrate to distant sites, cancer cells would need to adapt their behaviour in response to different tissue environments. Thus, it is essential to study… read more here.

Keywords: cell metastasis; metastasis; organotypic; cancer cell ... See more keywords
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Mature primary human osteocytes in mini organotypic cultures secrete FGF23 and PTH1-34-regulated sclerostin

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Published in 2023 at "Frontiers in Endocrinology"

DOI: 10.3389/fendo.2023.1167734

Abstract: Introduction For decades, functional primary human osteocyte cultures have been crucially needed for understanding their role in bone anabolic processes and in endocrine phosphate regulation via the bone-kidney axis. Mature osteocyte proteins (sclerostin, DMP1, Phex… read more here.

Keywords: culture; primary human; bone; mature ... See more keywords
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Circadian ATP Release in Organotypic Cultures of the Rat Suprachiasmatic Nucleus Is Dependent on P2X7 and P2Y Receptors

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Published in 2018 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2018.00192

Abstract: The circadian rhythms in physiological and behavioral functions are driven by a pacemaker located in the suprachiasmatic nucleus (SCN). The rhythms continue in constant darkness and depend on cell-cell communication between neurons and glia. The… read more here.

Keywords: atp release; organotypic; organotypic cultures; suprachiasmatic nucleus ... See more keywords