Micro-environmental cross-talk in an organotypic human melanoma-in-skin model directs M2-like monocyte differentiation via IL-10
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Immunology, Immunotherapy"
DOI: 10.1007/s00262-020-02626-4
Abstract: Preclinical assessment of novel therapies to fight cancer requires models that reflect the human physiology and immune response. Here, we established an in vitro three-dimensional (3D) reconstructed organotypic human melanoma-in-skin (Mel-RhS) model to investigate cellular… read more here.
Keywords: melanoma; mel rhs; organotypic human; model ... See more keywords
Organotypic human ex vivo models for coronavirus disease 2019 research and drug development
Sign Up to like & getrecommendations! Published in 2021 at "Current Opinion in Pharmacology"
DOI: 10.1016/j.coph.2021.04.006
Abstract: Since the discovery of SARS-CoV-2 in late 2019, intense research efforts on an unprecedented scale have focused on the study of viral entry mechanisms and adaptive immunity. While the identification of ACE2 and other co-receptors… read more here.
Keywords: research; organotypic human; drug; human vivo ... See more keywords