Overview and Comparison of Intestinal Organotypic Models, Intestinal Cells, and Intestinal Explants Used for Toxicity Studies.
Sign Up to like & getrecommendations! Published in 2018 at "Current topics in microbiology and immunology"
DOI: 10.1007/82_2018_142
Abstract: The intestine is a complex organ formed of different types of cell distributed in different layers of tissue. To minimize animal experiments, for decades, researchers have been trying to develop in vitro/ex vivo systems able… read more here.
Keywords: overview comparison; toxicity; organotypic models; toxicity studies ... See more keywords
Abstract 3826: Potency of cardiac glycosides by structure in organotypic models of pancreatic and ampullary carcinomas
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-3826
Abstract: Background: Organotypic models have emerged as an important preclinical model for developmental therapeutics in pancreatic and biliary cancer. Naturally derived cardiac glycoside in 2D monoculture exquisite potency, here we describe their activity in cancer and… read more here.
Keywords: potency; growth; cardiac glycosides; response ... See more keywords