Oridonin prevents epithelial-mesenchymal transition and TGF-β1-induced epithelial-mesenchymal transition by inhibiting TGF-β1/Smad2/3 in osteosarcoma.
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DOI: 10.1016/j.cbi.2018.09.013
Abstract: Osteosarcoma is the most common primary bone tumor with highly invasive characteristic and low long-term survival. Recently, epithelial-mesenchymal transition (EMT) is reported as a key event in cancer invasion and metastasis. Oridonin, a bioactive diterpenoid,… read more here.
Keywords: oridonin; mesenchymal transition; oridonin inhibited; epithelial mesenchymal ... See more keywords