Cellular effects and orientation of immobilized immunoglobulin are correlated to the charge-mediated influence of the antibody variable region.
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DOI: 10.1116/6.0004169
Abstract: Ligand binding to a cell receptor often insufficiently triggers cellular immune responses. Receptor clustering through cross-linking occurs when a ligand binds to two or more receptors, amplifying cellular responses. This is required in certain monoclonal… read more here.
Keywords: orientation immobilized; density; immobilized immunoglobulin; region ... See more keywords