DNA Origami: Scaffolds for Creating Higher Order Structures.
Sign Up to like & getrecommendations! Published in 2017 at "Chemical reviews"
DOI: 10.1021/acs.chemrev.6b00825
Abstract: DNA has become one of the most extensively used molecular building blocks for engineering self-assembling materials. DNA origami is a technique that uses hundreds of short DNA oligonucleotides, called staple strands, to fold a long… read more here.
Keywords: origami scaffolds; dna; dna origami; higher order ... See more keywords
Synthetic Translational Regulation by Protein-Binding RNA Origami Scaffolds
Sign Up to like & getrecommendations! Published in 2022 at "ACS Synthetic Biology"
DOI: 10.1021/acssynbio.1c00608
Abstract: Rational design approaches for the regulation of gene expression are expanding the synthetic biology toolbox. However, only a few tools for regulating gene expression at the translational level have been developed. Here, we devise an… read more here.
Keywords: translational regulation; rna origami; origami scaffolds; regulation ... See more keywords
Active generation of nanoholes in DNA origami scaffolds for programmed catalysis in nanocavities
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DOI: 10.1038/s41467-019-12933-9
Abstract: DNA origami tiles provide nanostructures for the spatial and temporal control of functional loads on the scaffolds. Here we introduce the active generation of nanoholes in the origami scaffolds using DNAzymes or light as triggers… read more here.
Keywords: origami scaffolds; dna origami; active generation; generation nanoholes ... See more keywords
Utilizing RNA origami scaffolds in Saccharomyces cerevisiae for dCas9-mediated transcriptional control
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac470
Abstract: Abstract Designer RNA scaffolds constitute a promising tool for synthetic biology, as they can be genetically expressed to perform specific functions in vivo such as scaffolding enzymatic cascades and regulating gene expression through CRISPR-dCas9 applications.… read more here.
Keywords: control; rna; scaffolds saccharomyces; rna origami ... See more keywords
RNA origami scaffolds facilitate cryo-EM characterization of a Broccoli–Pepper aptamer FRET pair
Sign Up to like & getrecommendations! Published in 2023 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkad224
Abstract: Abstract Cryogenic electron microscopy (cryo-EM) is a promising method for characterizing the structure of larger RNA structures and complexes. However, the structure of individual aptamers is difficult to solve by cryo-EM due to their low… read more here.
Keywords: structure; cryo; rna origami; origami scaffolds ... See more keywords