Site-specific MCM sumoylation prevents genome rearrangements by controlling origin-bound MCM
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DOI: 10.1371/journal.pgen.1010275
Abstract: Timely completion of eukaryotic genome duplication requires coordinated DNA replication initiation at multiple origins. Replication begins with the loading of the Mini-Chromosome Maintenance (MCM) complex, proceeds by the activation of the Cdc45-MCM-GINS (CMG) helicase, and… read more here.
Keywords: genome rearrangements; replication; site specific; origin bound ... See more keywords