A new original approach to the design of anticancer drugs based on energy-rich quadricyclanes
Sign Up to like & getrecommendations! Published in 2019 at "Russian Chemical Bulletin"
DOI: 10.1007/s11172-019-2516-1
Abstract: Quadricyclane derivatives are shown for the first time to be promising for application as anticancer drugs. The efficiency of such cage compounds is mainly due to thermal action on cancer cells resulting from a C—C… read more here.
Keywords: new original; original approach; anticancer drugs; approach design ... See more keywords
An original approach to measure ligand/receptor binding affinity in non-purified samples
Sign Up to like & getrecommendations! Published in 2022 at "Scientific Reports"
DOI: 10.1038/s41598-022-09217-6
Abstract: Several biochemical and biophysical methods are available to determine ligand binding affinities between a biological target and its ligands, most of which require purification, labelling or surface immobilisation. These measurements, however, remain challenging in regards… read more here.
Keywords: ligand receptor; membrane; original approach; measure ligand ... See more keywords