Molecular Origins of the Compatibility between Glycosaminoglycans and Aβ40 Amyloid Fibrils
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Molecular Biology"
DOI: 10.1016/j.jmb.2017.07.003
Abstract: The Aβ peptide forms extracellular plaques associated with Alzheimer's disease. In addition to protein fibrils, amyloid plaques also contain non-proteinaceous components, including glycosaminoglycans (GAGs). We have shown previously that the GAG low-molecular-weight heparin (LMWH) binds… read more here.
Keywords: charged residues; compatibility glycosaminoglycans; amyloid fibrils; origins compatibility ... See more keywords