Ormeloxifene, a nonsteroidal antifertility drug promotes megakaryocyte differentiation in leukemia cell line K562.
Sign Up to like & getrecommendations! Published in 2023 at "Cell biology international"
DOI: 10.1002/cbin.12017
Abstract: Ormeloxifene (ORM) (3,4-trans-2,2-dimethyl-3-phenyl-4-p-(β-pyrrolidinoethoxy) phenyl-7-methoxychroman), world's first nonsteroidal selective estrogen receptor modulator approved for contraception in India has been shown to have potential anticancer activities. Here, we show that ORM can induce megakaryocyte and myeloid (granulocytic) but not… read more here.
Keywords: leukemia cell; megakaryocytic differentiation; cell line; orm ... See more keywords
14‐3‐3ζ is crucial for the conversion of labile short‐term object recognition memory into stable long‐term memory
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.24894
Abstract: The consolidation of new memories into long‐lasting memories is multistage process characterized by distinct temporal dynamics. However, our understanding on the initial stage of transformation of labile memory of recent experience into stable memory remains… read more here.
Keywords: term; object recognition; orm; conversion labile ... See more keywords
Monitoring urinary orosomucoid in patients undergoing cardiac surgery: A promising novel inflammatory marker.
Sign Up to like & getrecommendations! Published in 2017 at "Clinical biochemistry"
DOI: 10.1016/j.clinbiochem.2017.07.010
Abstract: BACKGROUND Urinary biomarkers might provide non-invasive tool for monitoring of systemic processes. We aimed to investigate the time-course of urinary orosomucoid (u-ORM) excretion after cardiac surgery hypothesizing that u-ORM is an early and sensitive marker… read more here.
Keywords: surgery; orm; cardiac surgery; orm creat ... See more keywords
Modified Signaling of Membrane Formyl Peptide Receptors in NADPH-Oxidase Regulation in Obesity-Resistant Mice
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DOI: 10.3390/membranes13030306
Abstract: The signaling of membrane receptors is modified in obesity characterized by low-grade inflammation. The obesity-resistant state of organisms is poorly understood. We analyzed the generation of reactive oxygen species (ROS) initiated though membrane formyl peptide… read more here.
Keywords: nadph oxidase; obesity resistant; signaling membrane; orm ... See more keywords