THC/CBD oromucosal spray in patients with multiple sclerosis overactive bladder: a pilot prospective study
Sign Up to like & getrecommendations! Published in 2017 at "Neurological Sciences"
DOI: 10.1007/s10072-017-3148-6
Abstract: Lower urinary tract dysfunctions (LUTDs) are commonly reported in multiple sclerosis (MS) patients and are mainly related to neurogenic overactive bladder (OAB). The aim of this observational study was to assess the effect of a… read more here.
Keywords: overactive bladder; cbd oromucosal; bladder; thc cbd ... See more keywords
PTL401, a New Formulation Based on Pro-Nano Dispersion Technology, Improves Oral Cannabinoids Bioavailability in Healthy Volunteers.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of pharmaceutical sciences"
DOI: 10.1016/j.xphs.2017.12.020
Abstract: There is a growing clinical interest in developing and commercializing pharmaceutical-grade cannabinoid products, containing primarily tetrahydrocannabinol (THC) and cannabidiol (CBD). The oral bioavailability of THC and CBD is very low due to extensive "first-pass" metabolism.… read more here.
Keywords: cbd; bioavailability; thc cbd; thc ... See more keywords
Tetrahydrocannabinol and cannabidiol oromucosal spray in resistant multiple sclerosis spasticity: consistency of response across subgroups from the SAVANT randomized clinical trial
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Neuroscience"
DOI: 10.1080/00207454.2020.1730832
Abstract: Abstract Objective: To determine whether differences in disability status, spasticity severity, and spasticity duration at treatment start in patients with resistant multiple sclerosis (MS) spasticity might influence response to add-on tetrahydrocannabinol:cannabidiol (THC:CBD) oromucosal spray (nabiximols)… read more here.
Keywords: spasticity; severity; oromucosal spray; spasticity severity ... See more keywords
Effectiveness and tolerability of THC:CBD oromucosal spray as add-on measure in patients with severe chronic pain: analysis of 12-week open-label real-world data provided by the German Pain e-Registry
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Pain Research"
DOI: 10.2147/jpr.s192174
Abstract: Objective: To evaluate effectiveness, tolerability and safety of an oromucosal spray containing Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD), as add-on treatment in patients with severe chronic pain (SCP). Methods: Exploratory analysis of anonymized 12-week routine/open-label data… read more here.
Keywords: oromucosal spray; thc cbd; pain;
The Efficacy of Cannabis on Multiple Sclerosis-Related Symptoms
Sign Up to like & getrecommendations! Published in 2022 at "Life"
DOI: 10.3390/life12050682
Abstract: Multiple sclerosis (MS) is known as an autoimmune disease that damages the neurons in the central nervous system. MS is characterized by its most common symptoms of spasticity, muscle spasms, neuropathic pain, tremors, bladder dysfunction,… read more here.
Keywords: cannabis multiple; sclerosis related; oromucosal spray; efficacy cannabis ... See more keywords