Upfront DPYD Genotyping and Toxicity Associated with Fluoropyrimidine-Based Concurrent Chemoradiotherapy for Oropharyngeal Carcinomas: A Work in Progress
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DOI: 10.3390/curroncol29020045
Abstract: Simple Summary The combination of carboplatin and 5-fluorouracil (5-FU) is effective when used concurrently with radiotherapy for locoregionally advanced oropharyngeal carcinomas. DPYD polymorphisms can be associated with an increased risk of severe toxicity to fluoropyrimidines.… read more here.
Keywords: dpyd genotyping; dpyd; toxicity; upfront dpyd ... See more keywords
Fluid Biomarkers in HPV and Non-HPV Related Oropharyngeal Carcinomas: From Diagnosis and Monitoring to Prognostication—A Systematic Review
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DOI: 10.3390/ijms232214336
Abstract: Biomarkers are crucial in oncology, from detection and monitoring to guiding management and predicting treatment outcomes. Histological assessment of tissue biopsies is currently the gold standard for oropharyngeal cancers, but is technically demanding, invasive, and… read more here.
Keywords: biomarkers hpv; hpv; systematic review; oropharyngeal carcinomas ... See more keywords