Anaesthesia and orphan diseases: Yellow nail syndrome.
Sign Up to like & getrecommendations! Published in 2020 at "European Journal of Anaesthesiology"
DOI: 10.1097/eja.0000000000001169
Abstract: YNS typically involves a triad of thickened yellow nails, primary lymphedema and respiratory manifestations, which are variable in their presentation. It is an acquired condition of unknown cause, and rarely presents below the age of… read more here.
Keywords: yellow nail; nail; nail syndrome; diseases yellow ... See more keywords
Disease awareness or subtle product placement? Orphan diseases featured in the television series “House, M.D.” - a cross-sectional analysis
Sign Up to like & getrecommendations! Published in 2020 at "BMC Medical Ethics"
DOI: 10.1186/s12910-020-0463-x
Abstract: Background Approximately 7% of the general population is affected by an orphan disease, which, in the United States, is defined as affecting fewer than 1 in 1500 people. Disease awareness is often low and time-to-diagnosis… read more here.
Keywords: television series; house; orphan diseases; series house ... See more keywords
Innovative approach to determine overall survival (OS) benefit for orphan diseases using case match control analyses (CMCA): The PROPEL experience of pralatrexate in patients with relapsed/refractory (R/R) peripheral T-cell lymphoma (PTCL).
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.15_suppl.7521
Abstract: 7521Background: The challenges in conducting randomized studies in orphan diseases poses limitations on our ability to identify the most promising treatments. Randomized studies in this setting can... read more here.
Keywords: approach determine; determine overall; survival benefit; orphan diseases ... See more keywords