Articles with "orphan gpcr" as a keyword



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Constitutively active BRS3 is a genuinely orphan GPCR in placental mammals

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Published in 2019 at "PLoS Biology"

DOI: 10.1371/journal.pbio.3000175

Abstract: G protein–coupled receptors (GPCRs) play an important role in physiology and disease and represent the most productive drug targets. Orphan GPCRs, with their endogenous ligands unknown, were considered a source of drug targets and consequently… read more here.

Keywords: genuinely orphan; constitutively active; vertebrate brs3; gpcr ... See more keywords