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Published in 2019 at "PLoS Biology"
DOI: 10.1371/journal.pbio.3000175
Abstract: G protein–coupled receptors (GPCRs) play an important role in physiology and disease and represent the most productive drug targets. Orphan GPCRs, with their endogenous ligands unknown, were considered a source of drug targets and consequently…
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Keywords:
genuinely orphan;
constitutively active;
vertebrate brs3;
gpcr ... See more keywords