Articles with "ors cells" as a keyword



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Knockdown of HIF‐1&agr; inhibits the proliferation and migration of outer root sheath cells exposed to hypoxia in vitro: An involvement of Shh pathway

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Published in 2017 at "Life Sciences"

DOI: 10.1016/j.lfs.2017.10.011

Abstract: Aims: Outer root sheath (ORS) is a highly proliferative component of a hair follicle. This study is performed to investigate whether hypoxia‐induced elevation of hypoxia‐inducible factor (HIF)‐1&agr;, a transcriptional activator, contributes to the outgrowth of… read more here.

Keywords: shh pathway; proliferation; ors cells; hif agr ... See more keywords
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Double-stranded RNA induces inflammation via the NF-κB pathway and inflammasome activation in the outer root sheath cells of hair follicles

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Published in 2017 at "Scientific Reports"

DOI: 10.1038/srep44127

Abstract: Alopecia areata (AA), a chronic, relapsing, hair-loss disorder, is considered to be a T cell-mediated autoimmune disease. It affects approximately 1.7% of the population, but its precise pathogenesis remains to be elucidated. Despite the recent… read more here.

Keywords: outer root; inflammasome activation; root sheath; activation outer ... See more keywords
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The crosstalk between PTEN-induced kinase 1-mediated mitophagy and the inflammasome in the pathogenesis of alopecia areata.

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Published in 2023 at "Experimental dermatology"

DOI: 10.1111/exd.14844

Abstract: Alopecia areata (AA) is a T-cell-mediated autoimmune disease that causes chronic, relapsing hair loss; however, its precise pathogenesis remains to be elucidated. Recent studies have provided compelling evidence of crosstalk between inflammasomes and mitophagy-a process… read more here.

Keywords: pten induced; ors cells; inflammasome activation; crosstalk ... See more keywords

Preventative effects of antioxidants on changes in sebocytes, outer root sheath cells, and Cutibacterium acnes-pretreated mice by particulate matter: No significant difference among antioxidants

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Published in 2022 at "International Journal of Immunopathology and Pharmacology"

DOI: 10.1177/03946320221112433

Abstract: Objectives Particulate matter (PM) is an air pollutant that can damage human skin; antioxidants have shown some efficacy in alleviating PM-induced skin inflammation. We investigated the antioxidant effects of punicalagin, epigallocatechin-3-gallate (EGCG), and resveratrol on… read more here.

Keywords: acnes pretreated; sebocytes outer; pretreated mice; particulate matter ... See more keywords
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Application of extracellular vesicles from mesenchymal stem cells promotes hair growth by regulating human dermal cells and follicles

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Published in 2022 at "World Journal of Stem Cells"

DOI: 10.4252/wjsc.v14.i7.527

Abstract: BACKGROUND Dermal papillae (DP) and outer root sheath (ORS) cells play important roles in hair growth and regeneration by regulating the activity of hair follicle (HF) cells. AIM To investigate the effects of human mesenchymal… read more here.

Keywords: ors cells; stem; hmsc evs; hair growth ... See more keywords