Latent infection of Caenorhabditis elegans by Orsay virus induces age-dependent immunity and cross-protection
Sign Up to like & getrecommendations! Published in 2025 at "Nature Communications"
DOI: 10.1038/s41467-025-62522-2
Abstract: The C. elegans-Orsay virus pathosystem provides a powerful model for investigating the mechanisms that govern viral infection and immunity. Here, we focus on two key aspects of this interaction: the impact of lifelong latent infections… read more here.
Keywords: immunity; elegans orsay; latent infection; orsay virus ... See more keywords
Meta-analysis suggests evidence of novel stress-related pathway components in Orsay virus - Caenorhabditis elegans viral model
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DOI: 10.1038/s41598-019-40762-9
Abstract: The genetic model organism, Caenorhabditis elegans (C. elegans), shares many genes with humans and is the best-annotated of the eukaryotic genome. Therefore, the identification of new genes and pathways is unlikely. Nevertheless, host-pathogen interaction studies… read more here.
Keywords: analysis; caenorhabditis elegans; pathway components; orsay virus ... See more keywords
Punctuated Loci on Chromosome IV Determine Natural Variation in Orsay Virus Susceptibility of Caenorhabditis elegans Strains Bristol N2 and Hawaiian CB4856
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Virology"
DOI: 10.1128/jvi.02430-20
Abstract: Genetic variation determines the viral susceptibility of hosts. Yet, pinpointing which genetic variants determine viral susceptibility remains challenging. Here, we have exploited the genetic tractability of the model organism Caenorhabditis elegans to dissect the genetic… read more here.
Keywords: viral susceptibility; susceptibility; orsay virus; variation ... See more keywords