Synthesis of derivatives of podocarpane-type diterpenoids through Diels-Alder cycloaddition and photo-decarbonylation from unmasked ortho-benzoquinone
Sign Up to like & getrecommendations! Published in 2017 at "Tetrahedron"
DOI: 10.1016/j.tet.2017.02.032
Abstract: Derivatives of podocarpane-type diterpenoids, including cassane-type, abietane-type and totarane-type diterpenoids, are either widely distributed natural products or common intermediates in synthetic and medicinal chemistry. Although unmasked ortho-benzoquinone has been used in [4+2] cycloadditions in sparse… read more here.
Keywords: unmasked ortho; ortho benzoquinone; type diterpenoids; podocarpane type ... See more keywords
An Oxidative Dearomatization Approach to Tetrodotoxin via a Masked ortho-Benzoquinone.
Sign Up to like & getrecommendations! Published in 2021 at "Organic letters"
DOI: 10.1021/acs.orglett.1c03998
Abstract: Progress toward a stereoselective synthesis of tetrodotoxin (TTX) is presented. Oxidative dearomatization of a tetrasubstituted guaiacol arene yielded a masked ortho-benzoquinone that intercepted an acyl nitroso species generated in situ by the copper-catalyzed aerobic oxidation… read more here.
Keywords: masked ortho; oxidative dearomatization; ortho benzoquinone; tetrodotoxin ... See more keywords