Articles with "ortho oxide" as a keyword



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Synthesis and Pharmacological Evaluation of Enantiopure N-Substituted Ortho-c Oxide-Bridged 5-Phenylmorphans

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Published in 2022 at "Molecules"

DOI: 10.3390/molecules27248808

Abstract: The design of enantiopure stereoisomers of N-2-phenylcyclopropylmethyl-substituted ortho-c oxide-bridged phenylmorphans, the E and Z isomers of an N-cinnamyl moiety, and N-propyl enantiomers were based on combining the most potent oxide-bridged phenylmorphan (the ortho-c isomer) with… read more here.

Keywords: enantiopure; bridged phenylmorphans; substituted ortho; oxide bridged ... See more keywords