A Combination of Bio-Orthogonal Supramolecular Clicking and Proximity Chemical Tagging as a Supramolecular Tool for Discovery of Putative Proteins Associated with Laminopathic Disease.
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DOI: 10.1002/smll.202208088
Abstract: Protein mutations alter protein-protein interactions that can lead to a number of illnesses. Mutations in lamin A (LMNA) have been reported to cause laminopathies. However, the proteins associated with the LMNA mutation have mostly remained… read more here.
Keywords: bio orthogonal; proteins associated; tool; proximity chemical ... See more keywords
Hydrogen-bonded macrocycle-mediated dimerization for orthogonal supramolecular polymerization
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DOI: 10.3762/bjoc.21.10
Abstract: Orthogonal self-assembly represents a useful methodology to construct supramolecular polymers with AA- and AB-type monomers, as commonly used for covalently linked polymers. So far, the design of such monomers has relied heavily on three-dimensional macrocycles,… read more here.
Keywords: macrocycle; bonded macrocycle; polymerization; hydrogen bonded ... See more keywords