Combinatorial metabolic engineering using an orthogonal tri-functional CRISPR system
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DOI: 10.1038/s41467-017-01695-x
Abstract: Designing an optimal microbial cell factory often requires overexpression, knock-down, and knock-out of multiple gene targets. Unfortunately, such rewiring of cellular metabolism is often carried out sequentially and with low throughput. Here, we report a… read more here.
Keywords: engineering; crispr; tri functional; metabolic engineering ... See more keywords