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Published in 2018 at "Nature biotechnology"
DOI: 10.1038/nbt.4048
Abstract: Combinatorial genetic screening using CRISPR–Cas9 is a useful approach to uncover redundant genes and to explore complex gene networks. However, current methods suffer from interference between the single-guide RNAs (sgRNAs) and from limited gene targeting…
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Keywords:
crispr cas9;
orthologous crispr;
combinatorial genetic;
cas9 enzymes ... See more keywords