Articles with "orthologs across" as a keyword



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KinOrtho: a method for mapping human kinase orthologs across the tree of life and illuminating understudied kinases

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Published in 2021 at "BMC Bioinformatics"

DOI: 10.1186/s12859-021-04358-3

Abstract: Background Protein kinases are among the largest druggable family of signaling proteins, involved in various human diseases, including cancers and neurodegenerative disorders. Despite their clinical relevance, nearly 30% of the 545 human protein kinases remain… read more here.

Keywords: kinase orthologs; kinase; illuminating understudied; understudied kinases ... See more keywords