Bidirectional Regulatory Mechanisms of Disulfidptosis Govern Precision Targeting in Degenerative Bone Diseases and Osteosarcoma
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.70100
Abstract: Disulfidptosis is a newly identified form of programmed cell death closely associated with cystine metabolism abnormalities and cytoskeletal damage. Orthopedic diseases, such as degenerative conditions including intervertebral disc degeneration, osteoporosis, osteoarthritis, and malignant bone tumors… read more here.
Keywords: disulfidptosis; precision; orthopedic diseases; bidirectional regulatory ... See more keywords
Construction of a Computer-Aided Analysis System for Orthopedic Diseases Based on High-Frequency Ultrasound Images
Sign Up to like & getrecommendations! Published in 2022 at "Computational and Mathematical Methods in Medicine"
DOI: 10.1155/2022/8754693
Abstract: The area of medical diagnosis has been transformed by computer-aided diagnosis (CAD). With the advancement of technology and the widespread availability of medical data, CAD has gotten a lot of attention, and numerous methods for… read more here.
Keywords: ultrasound images; orthopedic diseases; analysis; method ... See more keywords
Research Progress of Senolytic Drugs in the Treatment of Orthopedic Diseases
Sign Up to like & getrecommendations! Published in 2025 at "Gerontology"
DOI: 10.1159/000543386
Abstract: Abstract Background: Orthopedic diseases, including osteoarthritis, osteoporosis, and age-related musculoskeletal disorders, significantly impact quality of life and are becoming increasingly prevalent with aging populations. A growing body of evidence highlights the role of cellular senescence… read more here.
Keywords: treatment; research progress; progress senolytic; orthopedic diseases ... See more keywords
Multiple applications of metal-organic frameworks (MOFs) in the treatment of orthopedic diseases
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2024.1448010
Abstract: Pharmacologic treatment of orthopedic diseases is a common challenge for clinical orthopedic surgeons, and as an important step in the stepwise treatment of orthopedic diseases, it is often difficult to achieve satisfactory results with existing… read more here.
Keywords: treatment; orthopedic diseases; frameworks mofs; treatment orthopedic ... See more keywords
Advances in cell therapy for orthopedic diseases: bridging immune modulation and regeneration
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2025.1567640
Abstract: Orthopedic diseases pose significant challenges to public health due to their high prevalence, debilitating effects, and limited treatment options. Additionally, orthopedic tumors, such as osteosarcoma, chondrosarcoma, and Ewing sarcoma, further complicate the treatment landscape. Current… read more here.
Keywords: cell therapy; treatment; orthopedic diseases; therapy orthopedic ... See more keywords
Progress in the application of epimedium and its major bioactive components in the treatment of orthopedic diseases
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2025.1628602
Abstract: Epimedium brevicornu (Yin Yang Huo), a widely used traditional Chinese medicinal ingredient, has garnered significant attention for its role in treating orthopedic diseases such as osteoporosis. Our work through network pharmacology and bioinformatics analysis, we… read more here.
Keywords: epimedium; treatment; orthopedic diseases; synapse ... See more keywords
Mesenchymal stem cell-derived extracellular vesicles, osteoimmunology and orthopedic diseases
Sign Up to like & getrecommendations! Published in 2023 at "PeerJ"
DOI: 10.7717/peerj.14677
Abstract: Mesenchymal stem cells (MSCs) play an important role in tissue healing and regenerative medicine due to their self-renewal and multi-directional differentiation properties. MSCs exert their therapeutic effects mainly via the paracrine pathway, which involves the… read more here.
Keywords: cell; extracellular vesicles; orthopedic diseases; msc derived ... See more keywords