Simplified and Rapid Determination of Primaquine and 5,6-Orthoquinone Primaquine by UHPLC-MS/MS: Its Application to a Pharmacokinetic Study
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DOI: 10.3390/molecules26144357
Abstract: The method for the determination of primaquine (PQ) and 5,6-orthoquinone primaquine (5,6-PQ), the representative marker for PQ active metabolites, via CYP2D6 in human plasma and urine has been validated. All samples were extracted using acetonitrile… read more here.
Keywords: plasma urine; determination primaquine; primaquine orthoquinone; orthoquinone primaquine ... See more keywords