Allosteric interactions via the orthosteric ligand binding sites in a constitutive G-protein-coupled receptor homodimer.
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DOI: 10.1016/j.phrs.2020.105116
Abstract: I interpret some recent data to indicate that co-operative effects take place between the (identical) orthosteric binding sites in a G-protein-coupled receptor dimer. In the current study, the reasonability of this concept was tested by… read more here.
Keywords: protein coupled; coupled receptor; binding sites; receptor ... See more keywords