A Brain‐Targeting NIR‐II Ferroptosis System: Effective Visualization and Oncotherapy for Orthotopic Glioblastoma (Adv. Sci. 13/2023)
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DOI: 10.1002/advs.202206333
Abstract: Near‐infrared‐II (NIR‐II) ferroptosis activators offer promising potentials in in vivo theranostics of deep tumors, such as glioma. However, most cases are nonvisual iron‐based systems that are blind for in vivo precise theranostic study. Additionally, the… read more here.
Keywords: orthotopic glioblastoma; brain targeting; ferroptosis; nir ferroptosis ... See more keywords
NIR-II Perylene Monoimide-Based Photothermal Agent with Strengthened Donor-Acceptor Conjugation for Deep Orthotopic Glioblastoma Phototheranostics.
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DOI: 10.1002/smll.202300203
Abstract: Extensive efforts have been devoted to the design of organic photothermal agents (PTAs) that absorb in the second near-infrared (NIR-II) bio-window, which can provide deeper tissue penetration that is significant for phototheranostics of lethal brain… read more here.
Keywords: orthotopic; orthotopic glioblastoma; deep orthotopic; agent ... See more keywords
Progesterone Is More Effective Than Dexamethasone in Prolonging Overall Survival and Preserving Neurologic Function in Experimental Animals with Orthotopic Glioblastoma Allografts.
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DOI: 10.1016/j.wneu.2019.01.113
Abstract: OBJECTIVE Dexamethasone (DEXA) has been widely used in the management of peritumoral brain edema. DEXA, however, has many systemic side effects and can interact negatively with glioma therapy. Progesterone (PROG), however, is a well-tolerated and… read more here.
Keywords: orthotopic glioblastoma; prog; overall survival; brain ... See more keywords