Anti-EGFR antibody cetuximab is secreted by oral squamous cell carcinoma and alters EGF-driven mesenchymal transition.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.07.035
Abstract: Genetic amplification, overexpression, and increased signaling from the epidermal growth factor receptor (EGFR) are often found in oral squamous cell carcinoma (OSCC) and thus EGFR is frequently targeted molecularly by the therapeutic antibody cetuximab. We… read more here.
Keywords: egf driven; egfr; oral squamous; oscc cells ... See more keywords
Differentiated embryo-chondrocyte 1, induced by hypoxia-inducible factor 1α, promotes cell migration in oral squamous cell carcinoma cell lines.
Sign Up to like & getrecommendations! Published in 2021 at "Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology"
DOI: 10.1016/j.oooo.2021.08.022
Abstract: Abstract Objective This study aimed to explore the correlation between differentiated embryo chondrocyte 1 (DEC1) and hypoxia-inducible factor 1α (HIF-1α) in OSCC and how they participate in tumor progression. Study Design An immunohistochemical staining method… read more here.
Keywords: oscc cells; dec1; hypoxia; cell ... See more keywords
Ubiquitin-specific protease 14 promotes radio-resistance and suppresses autophagy in oral squamous cell carcinoma.
Sign Up to like & getrecommendations! Published in 2020 at "Experimental cell research"
DOI: 10.1016/j.yexcr.2020.112385
Abstract: Oral squamous cell carcinoma (OSCC) is a common malignant tumor in the world. Radiotherapy is one of the standard therapies for patients with OSCC, but its clinical efficiency is limited due to radioresistance. In this… read more here.
Keywords: usp14 expression; oscc cells; usp14 knockdown; cell ... See more keywords
The inhibitory effect in oral squamous cell carcinoma cells by knocking down matrix metalloproteinase 9
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Oncology"
DOI: 10.1093/annonc/mdz238.018
Abstract: Abstract Background Extracellular matrix (ECM) is a basic step of tumor invasion and metastasis. Matrix metalloproteinase (MMPs) family is a kind of zinc-ion-dependent endopeptidase, which can degrade almost all protein components in the extracellular matrix,… read more here.
Keywords: invasion; cell carcinoma; oral squamous; squamous cell ... See more keywords
Spindly and Bub3 expression in oral cancer: Prognostic and therapeutic implications.
Sign Up to like & getrecommendations! Published in 2019 at "Oral diseases"
DOI: 10.1111/odi.13089
Abstract: OBJECTIVES Bub3 and Spindly are essential proteins required for the activation and inactivation of the spindle assembly checkpoint, respectively. Here, we explored the clinicopathological significance and the therapeutic potential of the opposing roles of the… read more here.
Keywords: spindly bub3; bub3 spindly; oscc cells; expression ... See more keywords
Upregulated circ_0002141 facilitates oral squamous cell carcinoma progression via the miR-1231/EGFR axis.
Sign Up to like & getrecommendations! Published in 2021 at "Oral diseases"
DOI: 10.1111/odi.14070
Abstract: OBJECTIVES The dysregulation of circular RNAs (circRNAs) is implicated in the progression of various cancers. This study was aimed at expounding the role and mechanism of hsa_circ_0002141 in the OSCC progression. MATERIALS AND METHODS Circ_0002141… read more here.
Keywords: oscc cells; mir 1231; progression; circ 0002141 ... See more keywords
PDZ-binding kinase inhibitor OTS514 suppresses the proliferation of oral squamous carcinoma cells.
Sign Up to like & getrecommendations! Published in 2023 at "Oral diseases"
DOI: 10.1111/odi.14533
Abstract: OBJECTIVE PDZ-binding kinase (PBK) has been reported as a poor prognostic factor and is a promising molecular target for anti-cancer therapeutics. Here, we aimed to investigate the effect of specific PBK inhibitor OTS514 on the… read more here.
Keywords: oscc cells; pdz binding; ots514; inhibitor ots514 ... See more keywords
MRTF-A/SRF signaling suppresses invasion of oral squamous cell carcinoma.
Sign Up to like & getrecommendations! Published in 2023 at "Oral diseases"
DOI: 10.1111/odi.14611
Abstract: BACKGROUND Serum response factor (SRF) and myocardial-associated transcription factor-A (MRTF-A) had different regulatory effects on the tumorigenesis and development in different cancers. However, the role of MRTF-A/SRF in oral squamous cell carcinoma (OSCC) remains to… read more here.
Keywords: oscc cells; cell; srf; mrtf srf ... See more keywords
miR-195 Inhibits Proliferation and Enhances Apoptosis of OSCC Cells via Targeting TLR4
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Healthcare Engineering"
DOI: 10.1155/2022/2270777
Abstract: The aim of this research was to assess the function of microribonucleic acid (miR)-195 in the apoptosis and proliferation of oral squamous cell carcinoma (OSCC) cells as well as its action mechanism. The downstream target… read more here.
Keywords: oscc cells; mir 195; tlr4; expression ... See more keywords
MicroRNA-96-5p promotes proliferation, invasion and EMT of oral carcinoma cells by directly targeting FOXF2.
Sign Up to like & getrecommendations! Published in 2020 at "Biology open"
DOI: 10.1242/bio.049478
Abstract: Recently, microRNA-96-5p (miR-96-5p) has been reported to function as both tumor suppressor and oncogene in several cancer types, including gastric cancer, hepatocellular cancer and lung cancer. However, the biological function of miR-96-5p and its precise… read more here.
Keywords: proliferation invasion; oscc cells; mir; invasion emt ... See more keywords
Long non-coding RNA XIST promotes the malignant features of oral squamous cell carcinoma (OSCC) cells through regulating miR-133a-5p/VEGFB.
Sign Up to like & getrecommendations! Published in 2022 at "Histology and histopathology"
DOI: 10.14670/hh-18-504
Abstract: OBJECTIVE Oral squamous cell carcinoma (OSCC) represents a frequently seen oral cavity malignancy, and the mechanisms of its occurrence and development remain unclear. The present work examined the expression and biological function of long non-coding… read more here.
Keywords: oscc cells; cell; oscc; mir 133a ... See more keywords