Identification of a Permissive Secondary Mutation That Restores the Enzymatic Activity of Oseltamivir Resistance Mutation H275Y
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DOI: 10.1128/jvi.01982-21
Abstract: The potential for influenza A virus (IAV) to cause pandemics makes understanding evolutionary mechanisms that impact drug resistance critical for developing surveillance and treatment strategies. Oseltamivir is the most widely used therapeutic strategy to treat… read more here.
Keywords: oseltamivir resistance; h275y; resistance; activity ... See more keywords
Assessment of influenza A (H1N1, H3N2) oseltamivir resistance during 2017–2019 in Iran
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DOI: 10.18502/ijm.v14i4.10241
Abstract: Background and Objectives: Neuraminidase inhibitors (NAIs) as an imperative antiviral for influenza prophylaxis and treatment are being consumed worldwide. Increasing use of these antivirals might be associated with drug resistance. Regarding the significance of these… read more here.
Keywords: iran; oseltamivir resistance; influenza; 2017 2019 ... See more keywords