Effect of multiple‐dose osimertinib on the pharmacokinetics of simvastatin and rosuvastatin
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DOI: 10.1111/bcp.13753
Abstract: We report on two Phase 1, open‐label, single‐arm studies assessing the effect of osimertinib on simvastatin (CYP3A substrate) and rosuvastatin (breast cancer resistance protein substrate [BCRP] substrate) exposure in patients with advanced epidermal growth factor… read more here.
Keywords: effect multiple; multiple dose; effect; osimertinib pharmacokinetics ... See more keywords